116 Comments
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Sharon's avatar

Very well-written, with points clearly stated, explains clearly this rare occurrence with the effects in daily life & development

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Shelly Huto's avatar

Thank you, thank you, thank you! As the mother of a son with 48XXXY, I feel like you ran through my brain and so brilliantly put together all the thoughts I haven’t been able to get to paper. I will be sharing far and wide.

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Hazel-rah's avatar

Thank You!!

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Lisa's avatar

I appreciate this so much! Thank you.

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Mark Christenson's avatar

Thank you for sharing this. I hate the fact the activists use conditions like your son’s to “prove” their ideology.

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Gala Mother's avatar

This is such a great article. thank you so much!

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Brigitte's avatar

Thank you very much for that explanations. Best regards Brigitte. Ich wish you all the best ♥️

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Dr. Sharon Fair's avatar

I've educated myself on Klinefelter's Syndrome ~ 30 years ago when I was referred to provide physical therapy to a patient who had it as a comorbidity (to the diagnosis for which I was providing physical therapy). Since then, I treated a few additional patients who also had Klinefelter's.

I was angry, but not shocked, when the "transgender cult" "claimed" people with this condition (as well as XXYY Syndrome, Turner's Syndrome, etc).

Thank you for writing this article. My best to you, your son and the rest of your family.

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Cary Cotterman's avatar

NPR is one of the primary providers of woke lies there is, broadcasting bias confirmation from leftist universities to millions of progressives. Pure "1984" radio.

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Savi_heretic33's avatar

Thank you for this educational article. It came at the right time. The anti science, anti women, anti Democratic, religious movement, has evolving talking points. They all repeat things from Google searches, as more scientific questions are posed. The latest is; that there are trans frogs and fish, intersex people etc. etc, and therefore their ideologies are real, yada yada yada, and I'm a, TERF, Nazi.. blah blah blah, you know, the usual BS. Personally, I don't think accepting the laws of nature are "radical," but maybe they actually are these days? Because you know, nature is a bigot. She is. She designed a perfect system of balance and harmony, that has worked for Millenia. We are constructs of her, regardless of belief. Many Trans women support the laws of nature, reality and science, while living their true authentic life. I support them, and admire their courage. It's just these radicals that are screaming the loudest. I'm sure this condition will be used soon in their talking points. And if you point out that it's a, genetic condition, you'll just be name- called and demonized for inserting reality into their magical- belief -system. Reality is tyranny to this extreme bunch.

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Christine's avatar

Thank you for sharing your story and educating me and others. It's good to learn actual scientific information that dispels yet another reason it's normal to be "born in the wrong body."

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Kelly Harding's avatar

This is interesting. In college I had a roommate with kleinfelfer. But she was a female, at least, that’s how she was living.

You could tell from looking at her that there was something off (very tall, gangly. Broad shoulders, wide jaw, etc), and she had behavioral/social issues too. I remember one day she revealed to us (it was an apartment style dorm with 4 girls) that she had a genetic condition called kleinfelter and that she had XXY chromosomes and penis but her parents raised her as a girl. She had breasts, so I don’t know if that’s a typical thing or not. One of the roommates was livid. The rest of us were compassionate but we didn’t really ask too much more about it and just tried to support her.

I didn’t realize this only affects males as that has been my only experience hearing of anyone with kleinfelter.

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Inch's avatar

I am XXY, I wasn’t diagnosed until my late teens. This was several decades ago, and as a male I was offered Testosterone first by weekly injections, and much later by gel. I’ve led a fairly normal adult life, yes, my muscle tone has always been lacking , I’ve always been tall and gangly, brain function wise my attention levels leave much to be desired but I’m intelligent and I’ve learnt to work around my attention limitations without alerting anyone. I have a well paid job and I’m happily married.

In my 20’s I was a bit undecided about my gender and when the gel became available, I went abroad for several years, had all types of relationships and through trial and error, I discovered I was a straight guy attracted to females. I did need to find this out for myself and it was a personal journey so I hadn’t told anyone back home before or since about this episode in my life. Also this was decades before the current obsession with gender.

I follow this Stack because I wonder what would have happened had I been born later and been diagnosed in this current period. I was so vulnerable back then, no hormones throughout my teenage years, I went through puberty 6 years after everyone else. I’m sure mentally I would have been open to convincing sounding professionals and who knows what agendas would have been pushed on to me. I am grateful I was left alone to make my own decisions and find my own way through a very difficult period.

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BJ's avatar

Hi, Inch - I'm also someone born with a condition affecting sexual development (intersex), presenting so that a chromosome test was immediately recommended and came back XY. Despite many surgeries and supplements, I didn't have a normal puberty, I sit to pee, and I remain sterile.

I certainly feel that I'm a different kind of male, after a personal journey that included being a father figure to more than a few kids, (including someone XXY who faces many of the challenges you face). I also was born to a time when a single agenda ruled: we can make him just like the other boys - my parents were convinced that fantasy was possible...

Intersex people most often identify over abnormal puberty, the difficulty of getting good medical care for the health of our bodies, and the lack of societal acceptance as [not the same kind of] M or F. Just as the hubris of the medical field convinced my parents (and still convinces many) to subject kids to genital 'conformance' surgeries as kids and pretend they're no different, the medical hubris now is psychological too.

We just need recognition to grow up unashamed of our bodies, not used as pawns or research subjects, or to win trans arguments on either side.

One way I think we can contribute to this topic is to remind folks that some of us were born to live literally on the margin of binary sex. Our presence is not a political threat, not a proof of a gender position, just a biological reality that should have social acceptance. Feel free to read my journal entries, a narrative exploration of the topic... sarisimpapers.substack.com

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Shannon's avatar

Your voice is critical in this conversation! Thank you for speaking out. I am quite familiar with XXY, as a loved one of mine is XXY. As you probably very well know, while there can be many developmental challenges, as described in the essay, the other side of the coin is that most guys with XXY lead pretty "normal" lives. (75% are undiagnosed in their lifetimes, so they go through their whole life not knowing about it). My loved one with XXY is also bright and intelligent.

I'm touched by your insights about how, considering your situation, you could have been vulnerable to having an agenda pushed on you. Thank you for speaking from your own experience.

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Eilatan's avatar

Thank you x

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Indio's avatar

Thank you for such an informative and enlightening article. My prayers are with you and your son. You have given us another view on this war that we are in. Shame on the ones that are using every aspect of life to support the insanity of so-called transgender ideology. It is indeed a cult and has become a religion to many. God has blessed your son with you as his parent as you have been blessed by him. Love, Indio.

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dd's avatar

I did not know that this is what Klinefelter was.

So, in essence, it's an extra chromosome.......but not an autosomal one? Humans have 44 autosomal chromosomes and 2 sex ones normally.

If instead of an extra sex chromosome, he had had an extra chromosome 21....that would have been Down Syndrome, I believe?

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Shannon's avatar

Yes, it's an extra sex chromosome. XXY is actually technically called 47XXY. Males in the general population are 46XY and females are 46 XX.

Females with an extra X chromosome have Turner syndrome (XXX)

Males with an extra Y have Jacob syndrome (XYY)

There's other sex chromosome variations such as 48XXXY, 49XXXXY, etc.

All fall under the umbrella of DSD's (Disorders of Sex Development). Many share similar developmental challenges and learning difficulties, as alluded to in the essay. *That's* why it's especially offensive to reference their biology for social gain - it's a population who already struggles in many areas, including speech/language. These populations are vulnerable to being taken advantage of because it's hard enough for them to speak for themselves.

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Kawika56's avatar

Thank you very much for this explanation and clarification.

I would like to add this to my document, if you agree.

Of course, you will get credit.

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Shannon's avatar

Which document are you referring to, Kawika56?

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dd's avatar

thank you

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